Cause and Effect of Sleep deprivation Essay Example for Free

Cause and Effect of Sleep deprivation Essay I am a firm believer that many factors such as our culture, our upbringing, and beliefs that we were introduced to all affects what we do, how we live and even what we eat! People in China, Vietnam and Switzerland have been known to eat dogs for thousands of year, some as a source of survival during war and famine while others eat it as a cuisine meaning it is a part of their regular diet! I’ve even read somewhere that people in China have been known to say that a huge reason they consume dog meat is to keep them warm in the harsh winters! Have they heard of a jacket and hot coco? They don’t see it any different from eating cows and pigs, but someone like me thinks that is disgusting! I see people all the time whose treat their dog as their best friend, I’ve heard that when you begin to grow attached to your dog you soon see them as people. I could never imagine it being okay to eat a dog! Functionalism has a lot to do with this also when you come to think of it. This tradition has been the norm in these places for years! It wasn’t until recently that proposed laws have been presented to implement a law that bans the eating of cats and dogs. Americans are truly the people of the land of the free and are strong believers that a dog is a mans best friend, in my opinion. Beating, not feeding, and mistreating dogs are all violations of the law, neglect, and animal abuse! I could not even imagine hearing a story of someone eating one! It is common knowledge here that dogs are like people and should be treated as such and so they are not put on a dinner plate, at least the way I view things. I strongly feel that our individual believes and knowledge is the reason we eat what we eat, they are culturally relative in more ways that one. This definitely is a beautiful thing as everyone can be their own person and act how they feel but this causes cultural diversity conflict all the time! Take this scenario for instance; two people are meeting for a blind date and obviously know nothing about one another. It becomes time to order and the woman is disgusted by the menu because everything is meat and fat of the meat from some type of animal, see, she’s vegetarian. The woman loves animals and does not believe in eating them and this sparks a conversation. Do you think it’s a good one as her date has already ordered the number four, which is the half slab of baby back ribs with chicken shish kabobs, and a side of pork rings? I can imagine that she stormed out of there after giving him a good lecture. Though her actions are understandable they aren’t quite right. Ethnocentrism would be the perfect would to explain that situation! The woman thinks that he beliefs are the right ones and that the man is wrong for eating what he loves to eat! Ethnocentrism is when you believe that your culture, your beliefs are better than everyone else’s and only yours make sense! This is a big reason there is conflict within cultures. Instead of using cultural relativism and trying to understand others point of view or even just accepting it as their choice we fight for what we think is the right way, the only way. Interactionism helps us understand that our mind plays a role in our how what our body does including why we eat or don’t eat what we eat. I love dogs, so I would vomit at the thought of eating one. However, once again this doesn’t mean I should hate someone that eats it as a dish at home. Being open and understanding can truly help because just as the conflict theory states that there is a power struggle between cultures, these cultures have the power to become knowledgeable of one another and ultimately obtain culture relativism.

Detection of Phenylbutazone in Race Horses

Detection of Phenylbutazone in Race Horses Forensic Bio analysis Detection of Phenylbutazone in Race Horses Phenylbutazone (C19H20N2O2 see figure 1 below) is a non-steroidal anti-inflammatory drug. Bute as it is more commonly known, is widely used for the treatment of bone, joint and soft tissue inflammation in horses. It was used in the treatment of ankylosing spondylitis in humans, but after serious issues and side effects was withdrawn. The main metabolites of Phenylbutazone (PBZ) are Oxyphenbutazone (OPBZ) and Hydroxyphenbutazone (HPBZ). As with most drugs Phenylbutazone has legal uses and also illegal uses. Despite Bute’s significant and anti-inflammatory effects, it has the capacity to affect racing performance in racehorses. The various racing regulatory bodies have varying permitted limits in pre and post-race samples, as they respect the need to discriminate between doping and the genuine therapeutic use of the drug. Figure 1. As such the need for stringent and accurate testing is crucial. There are various methods of testing and it is dependent upon the sample type which is best to use. Sampling in itself has issues blood tests are very invasive, but on the other hand gaining a urine sample is very awkward and hazard prone. Pharmacokinetics According to (Chay et al., 1984), (Lees, Maitho and Taylor, 1985; Maitho, Lees and Taylor, 1986), (Smith et al., 1987), (Landuyt, Delbeke and Debackere, 1993), the bioavailability of PBZ is in the range of 60% 91%. However it should also be noted that these studies showed variations in the rate of absorption between and within horses.(Gerring, Lees and Taylor, 1981) and (Maitho, Lees and Taylor, 1986), also showed that the rate of absorption is dependent on whether or not the horse has been fed. When food has been withheld from the treated horse for between 3 and 4 hours, before and after being dosed with PBZ, the maximum concentration in plasma according to (Maitho, Lees and Taylor, 1986), occurs at 4 to 6 hours. If the horse as constant access to fed, there is a small initial peak in in plasma concentration after 1 to 2 hours. This is then followed by a much larger absorption phase from 10 to 24 hours, which gives it a Tmax (amount of time that a drug is present at the maximum concentration in serum) of 12 to 14 hours. (Lees et al., 1986), explain that the distribution of PBZ from plasma to interstitial and trans-cellular fluids is limited, with the distribution volume being small 0.1 0.3 L/kg. Even though distribution is limited, it reaches sites of acute inflammation easily; this may be accountable to increased blood flow in the area and increased capillary permeability. (Rowland and Tozer, 2005), indicate that the distribution of the drug bound to plasma protein, in plasma, in extracellular fluid and in the rest of the body can be predicted. This is done by taking into account the fu (free fraction in plasma). In horses, the fu is 2% and the volume of distribution 0.17 L/kg. Using these figures Rowland and Tower, 2009 predicted that 29.4% of PBZ in the horses’ body will be in the plasma, 45.5% being present in the extracellular fluid and only 25% in the remainder of the body. Elimination of PBZ is principally dependant on hepatic metabolism. (Authie et al., 2010), showed that in test exercise conditions hepatic clearance became significantly decreased. (Authie et al., 2010), showed that renal clearance contributed to PBZ elimination. They found that elimination was shown to be similar at rest, 11.2% and at exercise, 12.9%. PBZ is lipophilic molecule, as such some of the drug is subsequently reabsorbed. As a result of this the urine, plasma concentration ratio in horses is low at around 2:1, (Gerring, Lees and Taylor, 1981). Analytical Methods HPLC (Grippa et al., 2000a) used HPLC (Reversed phase) to determine the presence and quantity of PBZ in equine serum. The serum was mixed with an internal standard, evaporated, re-suspended and then analysed, using a C-18 column which had been calibrated using acetonitrile/water/trifluoroacetic acid. The (Grippa et al., 2000a) method had a LOQ (limit of quantification) of 0.5 µg/ml and a LOD (limit of detection) 0.5 µg/ml. This method is only for the determination of the presence of PBZ. The only detector mentioned is a UV monitor which would simply say if it was present but not in what quantity it was is present. If an MS (mass spectrometer) was attached however, the PBZ could be quantified as well. There are however disadvantages to HPLC-MS and these are mainly associated with the MS. The molecular weight is not sufficient for identification and fragmentation is required. This can be achieved using MS-MS instruments such as triple Quadra-pole or ion trap. It can however only analyse volatile components The MS-MS works in two stages. The 1st stage MS isolates ion of interest and fragments and the 2nd stage produces mass spectrum of fragments. Electrochemical-based sensing coupled to selective extraction with molecularly imprinted polymers (MISPE) (Meucci et al., 2013), developed a new analytical method for detecting and quantifying PBZ in equine plasma. The technique is based on electrochemical sensing, they used disposable graphite based screen printed electrodes and DPVs (differential pulse voltammetry) for detection after the sample has gone through the MISPE (molecular imprinted solid phase extraction) procedure. Liquid Chromatography Electro-Spray Ionization Mass Spectrometry (LC–ESI-MS) can also be used as a detection method after elution from the MISPE (Harun, Anderson and Cormack, 2010). The accuracy of the (Meucci et al., 2013) method was shown to be more than 94% at 3 different concentrations. The LOQ (limit of quantification) was 0.01 µg/ml and the LOD (limit of detection) was 0.005 µg/ml. There method was validated using HPLC and the correlation of results was found to be r2 >0.999. This is a new method and with a new method comes criticism and the need to iron out the little flaws etc. This method has however been validated in comparison with HPLC. GC-MS (Gonzalez et al., 1996) method uses GC-MS to detect the presence of PBZ and OPBZ in equine plasma. Samples were prepared using an internal standard and the pH was adjusted to between 2 and 3. After missing and centrifugation, separated and evaporated to then undergo derivatisation. Helium was used as the carrier gas and the column was fused-silica cross-linked with methyl-silicone. The temperature of the detector and injector port was at a constant 280 °C, whereas the oven temperature was increased from 100 °C to 200 °C and then onto 300 °C. The LOD (limit of detection) for PBZ was 10ng/ml and for OPBZ 25ng/ml. The problems with GC-MS are mainly associated with the GC not the MS, these being that it can only analyse volatile components and most controlled substances i.e. drugs have to be derivatised prior to analysis. ELISA Elisa screening for drugs is a particularly sensitive and quick way of identifying if a drug is present. Due to the sensitivity of immunoassay screening, ELISA is usually used as a kind of ‘presumptive’ test before going ahead with the more expensive methods. Randox life sciences have developed an ELISA specifically for Phenylbutazone and Oxyphenbutazone (Kwiatkowski et al., 1989). It has an LOD of 2.01ng/ml and a calibration range of 0-90 ng/ml. Sample preparation is minimal with only a dilution required before the test can be performed. Preferred Method GC-MS has a better LOD than both HPLC and the MISPE methods, however sample preparation makes this method very laborious. The MISPE methods results were validated using HPLC and the correlation was very promising as a novel alternative to the more traditional HPLC and GC-MS methods. The MISPE method also had better LOQ and LOD than the HPLC method. Initially due to the high sensitivity and relative cheapness of the test I would first perform an ELISA to confirm the presence, provided enough sample was present. Providing a ‘presumptive’ positive had been gained, the preferred analytical method to detect PBZ in horse blood samples would then be the MISPE, (with Electrochemical-based sensing coupled to selective extraction with molecularly imprinted polymers method). Because it outranks even the gold standard techniques for ease of use and results gained. Internal standards An internal standard is a chemical substance which is added in a constant, consistent amount to the samples to be analyzed, the blank and calibration standards used in any given analysis. This substance is then used for calibration purposes by plotting the ratio of the signal of the analyte to the internal standard signal. This done in order to correct the loss of analyte, which occurs during sample preparation or at the point of inlet. (Grippa et al., 2000b) Used probenecid as the internal standard when looking for Phenylbutazone through HPLC analysis. However, no internal standard information was available for the internal standard used in the MISPE method. The internal standard is a very similar compound, but not identical to the analyte of interest in the samples. The internal standard should the then be affected in the same way during sample preparation etc. as the analyte of interest. Validation Method validation by HPLC analysis Method validation is the process of proving that an analytical method is acceptable for its intended purpose. Specificity, linearity, accuracy, precision, range, limit of detection, limit of quantification and robustness are all guidelines for validation. The electrochemical-based sensing method was compared with HPLC reference analysis in order to validate the method. The PBZ content of various spiked equine samples was tested using the two methods after the sample had been extracted using the MISPE procedure. The study’s findings with voltammetry-based sensing showed very good agreement with results obtained by HPLC analysis. Statistical tests on the data at the 95% significance level generated a correlation line with the following equation and correlation coefficient: y = 0.9997  ± 0.0043x + 0.00072  ± 0.012, r2 = 0.9998 for PBZ This showed an excellent correlation between the new developed method and the reference gold standard HPLC analysis. Therefore the proposed DPV-based method coupled to MISPE was shown to be very suitable for the quantitative analysis of PBZ in equine plasma. Linearity, LOQ/LOD and Accuracy and Precision Linearity Linearity is the sample concentration range where analyte response is linearly proportional to the concentration. The study performed a linearity test calibration curve with PBZ using standard solutions and the measurements were repeated nine times. The study’s criteria for r2 and g were r2 ≠¥ 0.99 and g≠¤10%. The regression lines were found to have the following equation: y = 0.04x + 0.01, r2 = 0.99 and g 3.7% for PBZ. Accuracy and precision Precision is the amount of scatter in results taken from multiple analysis. Accuracy is the Closeness of measured value to true answer. The precision of the study’s method was checked using replicates, 10 were performed on freshly prepared 0.5 g/ml solutions of PBZ. There were two types of precision and accuracy were assessed, within-day precision and accuracy and between-day. The within-day samples were assessed using blank plasma samples spiked with PBZ at 0.05 g/ml, 0.5 g/ml and 10 g/. These were extracted using the MISPE-procedure and analyse took place on the same day. Between-day samples were assessed using the same samples as the within-day tests. The acceptance criteria for accuracy were −20% to +10% of the theoretical concentration. The study found that the accuracy of the estimated PBZ concentration was more than 94% at three concentrations used as quality control samples. The precision expressed as inter-day coefficient of variation ranged from 2.6% to 6.5% and the intra-day CV% ranged from 1.5% to 5.0%. The coefficients of variation of 10 replicate analyses on freshly prepared 0.5 g/ml solutions were 1.5% for PBZ. LOQ and LOD The sensitivity of the method was shown as the limit of quantification. This limit was set at 10 times the standard deviation of the intercepts divided by the slope of the calibration curve. The limit of detection was set at 3.3 times the standard deviation of the intercepts divided by the slope of the calibration curve. The LOQ and LOD for PBZ was 0.01g/ml. This study found that the LOQ using this novel method are lower than those obtained with HPLC had a LOQ of 0.5 g/ml and GC/MS had a LOQ of 0.05 g/ml in analyses. The presented results compared favourably with those obtained with LC/MS/MS, which had a LOQ of 0.01 g/ml during analysis. Conclusion The comparison to all the known ‘Gold standard’ methods showed this method to be more sensitive and less expensive, both in terms of analysis time and instrumentation costs. References Authie, E. C., Garcia, P., Popot, M. A., Toutain, P. L., and Doucet, M. (2010) Effect of an endurance-like exercise on the disposition and detection time of phenylbutazone and dexamethasone in the horse: application to medication control. Equine Vet J. Vol.42(3), pp.240-7. Chay, S., Woods, W. E., Nugent, T. E., Weckman, T., Houston, T., Sprinkle, F., Blake, J. W., Tobin, T., Soma, L. R., Yocum, J., and et al. (1984) Population distributions of phenylbutazone and oxyphenbutazone after oral and i.v. dosing in horses. J Vet Pharmacol Ther. Vol.7(4), pp.265-76. Gerring, E. L., Lees, P., and Taylor, J. B. (1981) Pharmacokinetics of phenylbutazone and its metabolites in the horse. Equine Vet J. Vol.13(3), pp.152-7. Gonzalez, G., Ventura, R., Smith, A. K., de la Torre, R., and Segura, J. (1996) Detection of non-steroidal anti-inflammatory drugs in equine plasma and urine by gas chromatography-mass spectrometry. J Chromatogr A. Vol.719(1), pp.251-64. Grippa, E., Santini, L., Castellano, G., Gatto, M. T., Leone, M. G., and Saso, L. (2000a) Simultaneous determination of hydrocortisone, dexamethasone, indomethacin, phenylbutazone and oxyphenbutazone in equine serum by high-performance liquid chromatography. J Chromatogr B Biomed Sci Appl. Vol.738(1), pp.17-25. Grippa, E., Santini, L., Castellano, G., Gatto, M. T., Leone, M. G., and Saso, L. (2000b) Simultaneous determination of hydrocortisone, dexamethasone, indomethacin, phenylbutazone and oxyphenbutazone in equine serum by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications. Vol.738(1), pp.17-25. Harun, N., Anderson, R. A., and Cormack, P. A. (2010) Analysis of ketamine and norketamine in hair samples using molecularly imprinted solid-phase extraction (MISPE) and liquid chromatography-tandem mass spectrometry (LC-MS/MS). Anal Bioanal Chem. Vol.396(7), pp.2449-59. Kwiatkowski, S., Goodman, J. P., Stanley, S. D., Tai, C. L., Yang, J. M., Wood, T., Sturma, L., Woods, W. E., Tian, Z. G., Bertram, S., Tai, H. H., Weckman, T. J., Chang, S. L., Blake, J. W., Watt, D. S., Tobin, T., Mcdonald, J., Wie, S., Chung, R. A., Brecht, J. M., Conner, J. C., Dahl, P. A., Lewis, E. L., Prange, C. A., and Uboh, C. E. (1989) Immunoassay Detection of Drugs in Racing Horses .10. Detection of Phenylbutazone in Equine Blood and Urine by Particle Concentration Fluoroimmunoassay and Elisa. Research Communications in Substances of Abuse. Vol.10(2), pp.123-139. Landuyt, J., Delbeke, F. T., and Debackere, M. (1993) The intramuscular bioavailability of a phenylbutazone preparation in the horse. J Vet Pharmacol Ther. Vol.16(4), pp.494-500. Lees, P., Maitho, T. E., and Taylor, J. B. (1985) Pharmacokinetics of phenylbutazone in two age groups of ponies: a preliminary study. Vet Rec. Vol.116(9), pp.229-32. Lees, P., Taylor, J. B., Higgins, A. J., and Sharma, S. C. (1986) Phenylbutazone and oxyphenbutazone distribution into tissue fluids in the horse. J Vet Pharmacol Ther. Vol.9(2), pp.204-12. Maitho, T. E., Lees, P., and Taylor, J. B. (1986) Absorption and pharmacokinetics of phenylbutazone in Welsh Mountain ponies. J Vet Pharmacol Ther. Vol.9(1), pp.26-39. Meucci, V., Vanni, M., Sgorbini, M., Odore, R., Minunni, M., and Intorre, L. (2013) Determination of phenylbutazone and flunixin meglumine in equine plasma by electrochemical-based sensing coupled to selective extraction with molecularly imprinted polymers. Sensors and Actuators B: Chemical. Vol.179 pp.226-231. Rowland, M., and Tozer, T. N. (2005) Clinical pharmacokinetics/pharmacodynamics. Lippincott Williams and Wilkins. Smith, P. B., Caldwell, J., Smith, R. L., Horner, M. W., and Moss, M. S. (1987) The bioavailability of phenylbutazone in the horse. Xenobiotica. Vol.17(4), pp.435-43. B00222603Forensic Bio-analysisPage 1

Migraines: A Complex Disorder Essay -- Headaches Medical Neurology Pap

Migraines: A Complex Disorder If I can only make it to my bed, I'll be fine. My head hurts terribly. I would do anything to stop the pain. I've taken three extra strength Tylenols and the pain hasn't diminished at all. My head is spinning. Ever so often, the world around me turns dim and then bright. I close my eyes. I need to lie down, but I am driving. I feel nauseous. The pain that started on one side of my head is spreading as it pulsates. I squeeze my head and rub my temples, but the pain remains. I wish for a lobotomy. I wish somebody could stop the pain. I'm home. I run to my room. I tie a rag tightly around my head. It doesn't help. I press my head against a wall. I feel like vomiting again. I know relief is coming soon. I pass out. I am a Migraineur, and have been ever since I can remember. Migraine headaches are a type of vascular headache that affects 28 million Americans, 75 percent of whom are women 1) "http://www.ninds.nih.gov/health_and_medical/pubs/migraineupdate.htm">National Institute of Health, a good source of general information on migraine headaches. Annually, migraines cost the American taxpayers $13 billion in missed work and reduced productivity 1) "http://www.ninds.nih.gov/health_and_medical/pubs/migraineupdate.htm">National Institute of Health, a good source of general information on migraine headaches. Migraines are not a disorder unique to overworked Americans. In fact, the World Health Organization identified migraine among the world's top 20 leading causes of disability name="2">2) "http://www.w-h-a.org/wha/info.asp">World Health Alliance, a source of current articles about migraine headaches. According to the World Health Organization, aside from the physiological exp... ...lth Alliance, a source of current articles about migraine headaches 3) "http://archneur.ama-assn.org/issues/v57n8/ffull/nhn8476.html">Archives of Neurology, provides a historical perspective on topics related to neurology (3) 4) "http://www.achnet.org/understanding/">American Council for Headache Education, provides information on all types of headaches 5) "http://www.wfubmc.edu/neurology/migweb2/introduc.htm#INTRODUCTION">Wake Forest University Baptist Medical Center, lecture notes of a professor at the medical school 6) "http://www.migraines.org/myth/">MAGNUM, a good site for individuals who suffer from migraine headaches 7) "http://www.intelihealth.com/">Intelihealth, a site sponsored by Harvard Medical School 8) "http://www.neurologychannel.com/migraine/">Neurology Channel, provides a comprehensive look at migraine headaches

Texas Holdem Poker Casino v.s. Online Play Essay -- Compare Contrast E

Texas Holdem Poker Casino v.s. Online Play (All revisions in italics) So what’s this entire buzz about this new poker game? World poker tour play Krieger asks the question, â€Å"Why is it the most attractive card game to all the new comers and regulars alike (Krieger 4).† This new game is being played in almost every Casino from Atlantic City to Las Vegas Nevada. They game now has world championships and is played on TV and watched by millions around the world. This fascinating game known to many as Texas holdem poker is played by many in our homes, casinos, and now the every so popular game is attracting millions online. There are many things that are involved with this game and they include history, how to play, what to play, when to play or fold, how to read and how to bluff. These are only a few of the aspects that will be covered in this paper. So the question a rises for those who plan to make any money playing this game, and that is are the odds better online or in the casinos? Before we get into the odds of playing I will first introduce the modern day Texas holdem card game. According to poker author Krieger, the game originated its name from the first casino it was played in and how it was played (krieger 14). Krieger then adds that the game has only become popular in the last few years. The tournaments have been taking place over the last 40 or so years. These tournaments are the reason many believe the game has become so famous. The tournaments have been known to rake in over 2 million dollars for the winner and payouts for the top twenty positions (Krieger 17). Most of us are falling into this game for the first time, watching these holdem tourney's on television and holding poker night on the weekends. We have... ...to read people will open a lot of avenues of approach such as, knowing when to fold knowing when to bluff and even knowing when to play certain hands and how much to bet on them. Know these give always will allow a player to know what each player has without actually seeing the hand. All of these statements and reasoning above have pointed in the direction that if a player can use his or her skills playing in a casino is a better way to make money playing Texas holdem. In the casino a player can read his or her opponents, bluff his or her opponents out of their money, and have a more enjoyable atmosphere because he or she will be winning money. Where as when a player plays online the only thing he or she can play with are the odds and the people never become a factor. Playing in a casino is a better way to make more money playing Texas holdem than is playing online.

Marris Growth Maximisation Model

Assignment Set 2 Question 1 What are the principles of management? Answer There are fourteen principles of management laid by Henri Fayol. They are elaborated further below. Division of labour A particular task is divided into several units or segments, each performed by specialists in order to achieve efficiency. Authority and responsibility coexist Responsibility must be understood properly in order to achieve command in the business by taking the right decision at the right time for the right purpose. Unity of commandThere should be single chain of command in the organisational structure which means one person should report to only one boss Unity of direction Managers must be methodical and must approach with a single plan following the single universal approach to achieve goals Equity Management actions must be a combination of fairness, justice and empathy layered with the idea of productivity-based incentives. Order The entire process of productivity must balance on a discrete system which governs on the principles of desired output DisciplineManagement must elaborate through the entire chain of command the necessary of maintaining norms, rules and guidelines to enhance productivity and harmony in workplace Initiative The workers must find their job interesting so that they are enthusiastic about learning new responsibilities, thus bringing effectiveness. Fairness Various industrial laws and norms are established and governed by the respective legislative bodies to ensure a system of fairness, justice, equality is maintained within the industrial as well as organisational environment. StabilityProper schooling of guidelines, methodologies, and systems involved; creates team spirit, smoothness and enhances productivity. Thus an employee will always adjust himself or herself according to the dynamic reality. Scalar chain A strict and coordinated effort of inflow and outflow of information from top level to the lowest level of organisational hierarchy create s smoothness, review plans and solve problems faster. Subordination of individual interest to general interest Organisation’s interest must be prioritised at all cost because it affect the interest of many stakeholders.Espirit de corps Management must ensure the existence of team spirit, harmony and intense communication and accurate dissemination of information, trust among the employees. Centralisation and decentralisation Authority and power must centralise and decentralise accordingly although decentralisation is the trend nowadays in various existing multinational and national organisations. Question 2 What are the characteristics of leading? Answer The characteristics of leading are * Pervasiveness * Continuity * Human factor * Creativity Executive function * Delegating function Pervasiveness Characteristic of leading is required in all levels of organisation. Leading motivates all the levels in the organisation to coordinate with the CEO (leader). Continuity Leading is a continuous process happens everywhere and at anytime in the organisation. Its importance becomes higher when the organisation is undergoing a change. Human factor Leading directs and controls human factor of complexity and unpredictable nature in more of a disciplined, matured performer regarding fulfilment of rganisational goals and objectives. Creativity Differentiated thoughts and ideas are accumulated and processed through employees enrolled from different strata of the society brings matured creativity in order to project growth and development in the organisation. Executive function Leading implies that the followers execute the functions of organisation, which the leader and the follower agree is important for achieving the organisational goals and through it the individual goals. Delegating function Delegating is natural fallout of leading.It also follows that the leader trusts his or her followers and vice-versa. Mutual trust is the most important in leading and delegati on is largely based on that. Question 3 Briefly explain the four main approaches to organisational behaviour. Answer The main approaches to organisational behaviour are: * Human resource approach * Contingency approach * Productivity approach * Systems approach Human resource approach The organisation is for the people, by the people and with people. Humans are the integrated part of the organisation.Therefore growth and development is only possible when human resource are developed both internally and externally. Contingency approach Situation analysis is the vital part of the behavioural practices of organisation. Significant analysis of each situation prior to action helps to use all the current knowledge about people in the organisation in the most appropriate manner. Productivity approach Output per unit input is considered. Besides, economic inputs and outputs, we need to have human and social inputs and outputs in workplace, is the premise of this approach Systems approachThe systems view emphasizes the interdependence of people, technology, and socio-economic structure of organisation serves as a basis for co-ordinating activities to function as a whole effectively. Question 4 Explain the five major leadership styles as per the Managerial Grid Theory Answer The Managerial Grid Theory or also known as the Blake Mouton Framework builds on the Ohio and Michigan studies and creates a relative position that a leader prefers to take in most situations and thereby identifies his or her predominant style. The five major leadership styles are: * Impoverished leadership Country club leadership * Produce or perish leadership * Middle-of-the-road leadership * Team leadership Impoverished leadership It is the most haphazard, uncoordinated, reluctant, de-motivated style of leadership. It generates zero creativity, immense dissatisfaction and disharmony among employees. They have neither a high regard for creating systems for getting the job done nor for creating a w ork environment that is satisfying and motivating (low production/low people) Country club leadership It is mostly concerned about the needs and feelings of the members of the team.The main objective is making everyone happy instead of being focussed on the objectives and achieving results. A very relaxed environment exists but without direction and control (high people/low production). Produce or perish leadership Leaders believe that followers are simply a means to an end. They are generally strict and autocratic in nature. They believe frequent punishments can bring productivity and motivation in employees. (high production/low people) Middle of the road leadership Leaders settle for average performance and often believe that this is the most anyone can expect.In this case, neither production nor people needs are fully met. (medium production/medium people) Team leadership Leaders stress on needs related to production, quality and people with equal importance, because they believ e that each of them are the stakeholders of the organisation. This creates a team environment based on trust, and respect which leads to high satisfaction and motivation, resulting high production. (high production/high people) Question 5 List some of the commonly found perceptual biases. Answer The commonly found perceptual biases are as follows: Fundamental attribution error * Self serving bias * Selective perception * Halo effect * Contrasts effects * Projection * Stereotyping * Primacy(first-impression) effect * Recency effect * Self-fulfilling prophecy * Pygmalion effect * Golem effect Fundamental attribution error Tendency to underestimate the influence of external factors and overestimate the internal factors Self serving bias Tendency of people to attribute success to internal factors and failure to external factors, is known as self-serving biased perception Selective perceptionSometimes a person, or an object or an event stands out from the action. Faulty evaluation follow s after the action based on this selective perception. Halo effect Previous success creates a halo in our mind so that every time the same person, object or event returns, expectation remains premium about reproducing similar or better outcome. If the results fail to impress we generate biased judgements and attribute it to some outside factors rather to accept the inabilities. Contrast effects. Individuals do not evaluate a person in isolation.There is always a tendency of comparison which depicts high contrast in values and actual actions of the organisation, generating various prejudices. Projection We tend to feel and see that others are like us, and taking decisions on the premise that others want what we want, such perception is called projection. Stereotyping Judging someone on the basis of our perception of the group to which the person belongs is defined as stereotyping. It simplifies the complex world. But when we inaccurately stereotype, various mistakes and misunderstand ings cloud the right perception.Primacy effect First impression-lasting effect theory, the tendency to form lasting opinions about an individual based on the initial perceptions. This error is generally found formal interview sessions. Recency effect When we summarise a series of action taken by a person recently and decide its effectiveness in reality, we perceive with recency effect. Self-fulfilling prophecy It is a tendency for someone’s expectations about another to cause that person to behave in a manner consistent with those expectations.It can of two types * Pygmalion effect- manager has high expectations of his employee and therefore grades him as the topper although the facts indicate otherwise * Golem effect- the same manager evaluates his top performer as third, because his expectation from him is not high although the facts indicate otherwise Question 6 Suppose you are the Team Manager in a multinational company with team strength of 12 members. You are given the responsibility of ensuring that the team gives excellent performance or results. What are the key issues you have to handle in team building? AnswerThe key issues needed to handle while building a proper team are: * having clear expectations and context * commitment * team design and competence * charter of performance * control and coordination * collaboration * communication * consequences * creative innovation * cultural change Having clear expectations and context The team should get sufficient resources like people, time and money. The team need to understand the role and importance of their work and their strategic existence. Commitment All team members must oath in sincerity and recognised contribution in order have growth and development.They should enthusiastic, excited and challenged by the opportunity. Team design and competence There should continuous evaluation of the structure and reason of existence so that competencies are evolved and used to achieve results faster a nd in superior quality. Charter of performance The team must define its goals, the outcomes, the timelines, measuring success, and the process to accomplish tasks. Equally , the support of the top management is the precondition Control and coordination The team should have sufficient freedom and mechanism for self regulation and coordination.The top management must ensure the existence of such team spirit, address the challenges through incentives and motivation. Collaboration The team goals should be a collaborative one, and should establish norms so that collaboration becomes easy and effective. Communication The members must continuously communicate among themselves because it is the mother of all issues that is needed to be solved immediately as soon as the team formation occurs. Consequences Team members must be accountable and should feel responsible for the achievement and they should inherently get the idea of consequences of not achieving it. Creative innovationThe team mus t continuously innovate with the freedom of creativity in order to sustain for long run. Cultural change Teams need flat organisational structure, rewards and recognition and training and development of a high order. Traditional companies are not designed for effective team operation. Acknowledgement I would like to thank our honourable lecturers Mr. Indranil Bhattacharya and Miss Sumita Haldar for extensive cooperation and support in order to establish focused effort in completion of the assignment successfully. I would also like to thank my mates and Sikkim Manipal University for extensive cooperation and support.

Data protection Act 1998 Essay

The Data Protection Act 1998 (DPA) is a United Kingdom Act of Parliament which defines UK law on the processing of data on identifiable living people. It is the main piece of legislation that governs the protection of personal data in the UK. Although the Act itself does not mention privacy, it was enacted to bring UK law into line with the EU data protection directive of 1995 which required Member States to protect people’s fundamental rights and freedoms and in particular their right to privacy with respect to the processing of personal data. In practice it provides a way for individuals to control information about themselves. Most of the Act does not apply to domestic use, for example keeping a personal address book. Anyone holding personal data for other purposes is legally obliged to comply with this Act, subject to some exemptions. The Act defines eight data protection principles. It also requires companies and individuals to keep personal information to themselves. The 22 August 1998 Act replaced and consolidated earlier legislation such as the Data Protection Act 1984 and the Access to Personal Files Act 1987. At the same time it aimed to implement the European Data Protection Directive. In some aspects, notably electronic communication and marketing, it has been refined by subsequent legislation for legal reasons. The Privacy and Electronic Communications (EC Directive) Regulations 2003 altered the consent requirement for most electronic marketing to â€Å"positive consent† such as an opt in box. Exemptions remain for the marketing of â€Å"similar products and services† to existing cu stomers and enquirers, which can still be permissioned on an opt out basis. The Act’s definition of â€Å"personal data† covers any data that can be used to identify a living individual. Anonymised or aggregated data is not regulated by the Act, providing the anonymisation or aggregation has not been done in a reversible way. Individuals can be identified by various means including their name and address, telephone number or Email address. The Act applies only to data which is held, or intended to be held, on computers (‘equipment operating automatically in response to instructions given for that purpose’), or held in a ‘relevant filing system’. [3] In some cases even a paper address book can be classified as a ‘relevant filing system’, for example diaries used to support commercial activities such as a salesperson’s diary. The Freedom of Information Act 2000 modified the act for public bodies and authorities, and the Durant case modified the interpretation of the act by providing case law and precedent.[4] The Data Protection Act creates rights for those who have their data stored, and responsibilities for those who store, process or transmit such data. The person who has their data processed has the right to: [5] View the data an organisation holds on them. A ‘subject access request’ can be obtained for a nominal fee. As of January 2014, the maximum fee is  £2 for requests to credit reference agencies,  £50 for health and educational request, and  £10 per individual otherwise, [6] Request that incorrect information be corrected. If the company ignores the request, a court can order the data to be corrected or destroyed, and in some cases compensation can be awarded. Require that data is not used in any way that may potentially cause damage or distress. Require that their data is not used for direct marketing.

Essay on Great Gatsby Divisadero Landscape - 649 Words

In both of the books Great Gatsby and Divisadero, both of the authors Michael Ondaatje and F. Scott Fitzgerald they tend to show a Drama issue movie based. Where they both show real life situations and what they try to do and what we would typically would do if we were in there shoes. Fitzgerald shows the American Dream we all try to achieve throughout our life. Gatsby tries to show off to Daisy with all the power and money he gets in the book even though she is married he doesnt stop. Then in the book Divisadero, its same only difference that the orphan character, Cooper starts feelings for Anna. Just like in Gatsby situations which he is stuck with Daisy. So, with that all being told, both of the stories fall under how they happened†¦show more content†¦In the Great Gatsby the setting is an more wealthy area, which can be seen through the wealthy lifestyles of the main character Jay Gatsby. Gatsby throws parties every Saturdays, gambles, and received most of his money by stealing, and gambling. Gatsby reflected new money, and was motivated by the love he had for his long lost love Daisy, who was a married woman. Jay Gatsby started off poor which was shown in the setting of a farm where he worked for the farm owner, and that setting help develop Gatsbys character because that farm and the owner inspired him to work hard to become rich. Later on, he does achieve his goal, and it is shown through the wealth he has acquired. In Divisadero, Anna and Claire both live in wealthy areas, Anna and Claire both had resided in San Francisco. Anna had moved to France after her father found out she was having sex with Cooper. Cooper was not so lucky as Anna, because after being nearly beaten to death by Annas father ,he relocates to Las Vegas where he starts to gamble. Cooper lives in a hotel where he meets a drug addict, Bridget, who he thinks is Anna. Annas family is very wealthy as we can see when she moves to the French countryside, after having some family problems with her dad. Cooper isnt so lucky in the wealthy category, because he ends up in Las Vegas. Although Cooper does make a lot of money gambling in Las Vegas he is forced to leave due to life threatening issues.

What Is a Monopoly

Anyone whos ever player the popular board game Monopoly has a pretty good idea of what a monopoly is. In the board game, one of the goals is to own all of the properties of a particular color, or, in economic terms, to have a monopoly on properties of a particular color. Its also the case that, when a player has a monopoly on a set of properties, the rents on those properties go up. This is also a realistic feature of the game since its generally true that monopolies lead to higher prices. A monopoly is simply a market with only one seller and no close substitutes for that sellers product. Technically, the term monopoly is supposed to refer to the market itself, but its become common for the single seller in the market to also be referred to as a monopoly (rather than as having a monopoly on a market). Its also fairly common for the single seller in a market to be referred to as a monopolist. Monopolies arise because of barriers to entry that inhibit other companies from entering the market and exerting competitive pressure on the monopolist. These barriers to entry exist in multiple forms, so there are a number of specific reasons that monopolies can exist. Ownership of a Key Resource Government Franchise Intellectual Property Protection free-rider problem Natural Monopoly club goods In all cases, there is a bit of ambiguity surrounding the market definition for determining whether a company is a monopolist. For example, while it is certainly true that Ford has a monopoly on the Ford Focus, it is certainly not the case that Ford has a monopoly on cars overall. The market definition question, which rests on what is considered to be a close substitute, is a central issue in most monopoly regulation debates.